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Wednesday, June 24, 2009

Applied Neutriceuticals New Designer, The One

Applied Neutriceuticals in my humble opinion seems to be a straight shooting, honest company whose goal is to produce progressive supplements with good real world results.... and no I do not work for them or any supplement company for that matter. My judgment about this company is not based on experience being that I have not tried any of AN's supplements. It is based upon the buzz they have created on the internet and the fact that they list their ingredients with the actual ingredients and amounts. They have also made their way in to vitamin shoppe which leads me to believe they are pretty hot right.
Ok, enough BS, The One! that's what I want to talk about. The One is described as a pro-hormone to DHT that is 3-5 times more potent than testosterone. It also comes with Second Gear which is a support supplement to be taken during your cycle. The One contains 22.5mg of the active ingredient 17a-methyl-etioallocholan-17b-ol-3-hydroxyimine which is taken twice a day. The molecule is pictured below.
What you are looking at is a precursor to a hormone but it's not exactly DHT. It's methyl DHT! This is a strait forward pro-hormone with simple chemistry. This is methyl DHT that has been reacted with a hydroxylamine. The hydroxylamine reacts with the ketone at the third position and produces an oxime which is the N-OH double bonded at the third position in the molecule above. Overly simplified paint version of the reaction below.
So now you have an oxyimine what's the big deal? Well the big deal my friend is that you have a molecule which is not methyl DHT.... Place it in an acidic environment such as... your stomach and... BOOM that good old oxyimine is cleaved and replaced with a ketone. In lay man's terms your stomach acid turns The One into methyl DHT. AN claims that this is 3-5 times more powerful than testosterone well according to a research article provided by Methyl DHT is 3.8 times more anabolic and 1.6 times more androgenic than testosterone. I would be a little scared actually taking DHT but other than that sounds pretty good for a legal alternative.

Once you have finished your cycle of The One you need to finish it off with a nice PCT, so grab your second gear. Since second gear is nothing novel I'll make this quick. Second gear is a 550mg blend of Milk Thistle, Avena Sativa 10:1, 13-C (Indole-3-Carbinol), 6-Bromodione (6-bromo-etioallocholan-4-ene, 17-dione;50% Alpha/50% Beta)*.......50mg. Let's break this down milk thistle to support the liver, like it. Avena Sativa to prevent your elevated hormone levels from being bound by SHBG, like it. 13-c possibly anti-carcinogenic, possibly anti-estrogenic, I'll take it. 6-bromodione with a 50/50 racemic index of alpha and beta isomer, from what I hear one isomer is an aromatase inhibitor and the other is androgenic, love it!

RIP Big Bapper and Swolecat

Two bodybuilders with very popular reputations amongst online bodybuilding communities have passed away this month. Both contributed vast amounts of information and support to the online community. My heart and prayers go out to the families and all of those affected by their deaths.

Thirty-two year old Seamus Warrington (pictured above) AKA Big Bapper on the forum, passed away Friday June 19, 2009 in a local hospital. According to BigA @ a blood clot which had formed in his leg from a previous injury travelled to his heart forming a blockage. Warrington leaves behind a wife and young daughter. A memorial fund for his family has been set up in his name @ .

Pictured above is 37 year old Christopher Lear Janusz AKA Swolecat on the forums. The following obituary was take from internet websites.
Christopher Lear JanuszApril 2, 1972 ~ June 10, 2009SEASIDE, CALIFORNIA - Christopher Lear Janusz, 37, passed away June 10, 2009. He was born April 2, 1972 in Alexandria, LA and had been a lifelong resident of Monterey County.Chris was professionally known as "Swolecat". He was an avid sports fan who loved being active with his son's sports activities.He is survived by his wife, Mariela Janusz of the family home in Seaside; son, Jordan Christopher of Seaside; parents, Greg and Julia Janusz of Seaside; and paternal grandmother, Felicia Janusz of Miami, Florida. He is also survived by an aunt, George Alice Dupuy of Marksville. Greg's mother, Julia, is the former Julia DeCuir of Markville, the daughter of the late Forrest and Hina DeCuir.A Memorial Mass will take place on Tuesday, June 16, 2009, 11AM at Our Lady of Mt. Carmel Church, 9 El Caminito, Carmel Valley, CA 93924.Memorial contributions may be made to the donor's favorite charity.

German American Technologies FinaJet??????

Ok, so I am always excited to see a new prohormone or DS on the market. Usualy when there is a novel compound produced there is a ton of hype before it is released. Well when I found German American Technologies' (GAT) FinaJet with a completely different nomenclature and no hype before its release I knew something wasn't right. We know most of these companies like to find the craziest nomeclature possible... to elude big brother? to sound realy cool and new to the consumer? I'm guessing all of the above!
Now let's dive into the claimed compound, (drum roll please)

17b-Hydroxymethylandrost-4,9 11-Trien-1,4-Dien-3-One

First off anyone that took an organic chem class will notice they named the 4-ene molecule twice which is retarded to say the least. This would be a cross between dianabol/methandrostenolone and trenbolone. It could be describer as trenbolone with a double bond added @ the 1 position and a 17 alpha alkylation(17aa) for oral availability. The structure would look like this crude drawing I made in paint.
UPDATE: Spartan300 at anabolicminds also pointed out an oversight or mine... At the 10th position, which is the top carbon in between the first and second ring, there are five bonds which is impossible, carbon is only stable with four bonds. Therefore with the nomenclature prodvided, this molecule is PHYSICALY IMPOSSIBLE. GAT would have had to claim 19-nor or replace androst with estra in the name in order for this mollecule to actualy be possible.

So we have a cross between dbol and tren dosed @ 152mg/day... now I like increasing muscle mass just as much as the next guy, but increasing my liver mass is not cool! I beleive that if GAT had the capital to custom synthesize this compound they would have had the capital or atleast the man power to hype the shit out of this on the boards. Big3upgrade @ has a post that claims he had called the company and the person answering the phone claimed "Finajet is a hybrid between Estra/19-nor and TRENADROL. Finnajet is not Estra/19-nor, and its not trenadrol, its "In between". He than said they figured out a way to mix both of those compound together to make finajet. Wow thanks GAT very scientific answer.

My guess is its boldione-> 1,4-androstadiene-3,17-dione, the dieneolone precursor-> Estra-4,9-diene-3,17-dione, considering they claim there is a methyl group there is probably the epistane compound ->2a,3a-epithio-17a-methyl-5a-androstan-17b-ol as well. Why didn't they just list those? IDK it seems like a pretty good combo.

Tuesday, June 23, 2009

Competitive Edge Labs Release Suppress-C

Competitive Edge Labs AKA CEL is known for producing good quality clones of pre-existing pro-hormones. Suppress-C which is trans dermal cortisol suppressant was announced in April on's forum and is now available on their website.

This product is Androst-5-Ene-3b,7b,17b-Triol, commonly referred to as B(beta)-androstenetriol, abbreviated as BAET. BAET is most simply described as DHEA with an extra hydroxyl group or -OH molecule added at the seventh position of the molecule. The structure is shown below.

BAET shows immune system support and antiglucocorticoid effects in mice. Common sense would suggest that the antiglucocorticoid effect is responsible for the suppression of... you guessed our glucocorticoid friend cortisol. Being that cortisol can increase body fat, this supplement should reduce this unwanted flab that us fat Americans keep accumulating, with proper diet and exercise of course! This molecule is suspended in a proprietary blended trans dermal matrix or Isopropyl Alcohol, Benzyl Alcohol, Octyl Salicylate, Triglyceride Complex, Water, D-Limonene, Carbomer.